1633009-87-6
1633009-87-6
Chemical Structure
BI 689648
- CAS No.: 1633009-87-6
- Formula:C16H18N4O2
- Molecular Weight:298.34
IUPAC Name: 6-(5-(methoxymethyl)pyridin-3-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
InChIKey: DJFDCVNQDFICKV-UHFFFAOYSA-N
SMILES: O=C(N1CCCC2=C1N=CC(C3=CC(COC)=CN=C3)=C2)N
Biological Activity: BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively.
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BI 689648 | 99.20% | BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively. | ||||||||||||||||||||
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BI 689648 (Standard) | ≥98% | BI 689648 (Standard) is the analytical standard of BI 689648 (HY-101217). This product is intended for research and analytical applications. BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.54
HY-149966PB131 -
Similarity Score 0.54
![[3,3'-Bipyridine]-5,5'-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w112868.gif)
HY-W112868[3,3'-Bipyridine]-5,5'-dicarboxylic acid -
Similarity Score 0.52
HY-W4565905-(5-Methylpyridin-3-yl)isophthalic acid -
Similarity Score 0.51
HY-W1123035-(5-Aminopyridin-3-yl)isophthalic acid -
Similarity Score 0.51
HY-159074Cot-IN-5 -
Similarity Score 0.51
HY-W953618CRBN ligand-628 -
Similarity Score 0.51
HY-W952783CRBN ligand-640 -
Similarity Score 0.51
HY-W953781CRBN ligand-476 -
Similarity Score 0.51
HY-W1123025-(5-Carboxypyridin-3-yl)isophthalic acid -
Explore the MedChemAI to find more analogs
![[3,3'-Bipyridine]-5,5'-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w112868.gif)
