1637253-79-2
1637253-79-2
Chemical Structure
EGFR/HER2-IN-9
- CAS No.: 1637253-79-2
- Formula:C25H25ClFN5O4
- Molecular Weight:513.95
IUPAC Name: (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-((4aR,7aS)-hexahydro-6H-[1,4]dioxino[2,3-c]pyrrol-6-yl)but-2-enamide
InChIKey: REGOTSLWVKSZRG-GYQWKJCYSA-N
SMILES: COC(C(NC(/C=C/CN1C[C@@]2([H])[C@@](OCCO2)([H])C1)=O)=C3)=CC4=C3C(NC5=CC(Cl)=C(C=C5)F)=NC=N4
Biological Activity: EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor with IC50s of 3.2, 8.3 and 14 nM against EGFR, EGFR T790M and HER2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR/HER2-IN-9 | 98.73% | EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor with IC50s of 3.2, 8.3 and 14 nM against EGFR, EGFR T790M and HER2, respectively. | ||||||||||||||||||||
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References
Keywords
