1660117-38-3
Chemical Structure
BRD4 Inhibitor-10
- CAS. Nr.: 1660117-38-3
- Formula:C25H27N5O2
- Molecular Weight:429.51
IUPAC Name: (S)-2,4-dimethyl-6-(1-(1-phenylethyl)-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl)pyridazin-3(2H)-one
InChIKey: QNFGQQDKBYVNAS-KRWDZBQOSA-N
SMILES: CN1C(C(C)=CC(C2=NC3=CN=C(C=C3N2[C@H](C4=CC=CC=C4)C)C5CCOCC5)=N1)=O
Biological Activity: BRD4 Inhibitor-10 is a potent BRD4-BD1 inhibitor with an IC50 of 8 nM. BRD4 Inhibitor-10 interferes with the recognition of acetylated histone marks by the BRD4 bromodomain through inhibiting the interaction between BRD4-BD1 and tetra-acetylated histone H4 peptide. BRD4 Inhibitor-10 is used for research on BRD4-mediated epigenetic regulation and cancer[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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BRD4 Inhibitor-10 | 99.52% | BRD4 Inhibitor-10 is a potent BRD4-BD1 inhibitor with an IC50 of 8 nM. BRD4 Inhibitor-10 interferes with the recognition of acetylated histone marks by the BRD4 bromodomain through inhibiting the interaction between BRD4-BD1 and tetra-acetylated histone H4 peptide. BRD4 Inhibitor-10 is used for research on BRD4-mediated epigenetic regulation and cancer. | ||||||||||||||||||||
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Similarity Score 0.52
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