166095-95-0
Chemical Structure
BMS-191095 hydrochloride
- CAS No.: 166095-95-0
- Formula:C22H22Cl2N4O2
- Molecular Weight:445.34
IUPAC Name: (3R,4S)-4-(((1H-imidazol-2-yl)methyl)(4-chlorophenyl)amino)-3-hydroxy-2,2-dimethylchromane-6-carbonitrile hydrochloride
InChIKey: TZLMTXNZECPICU-JUDYQFGCSA-N
SMILES: CC(O1)(C)[C@H](O)[C@@H](N(CC2=NC=CN2)C3=CC=C(Cl)C=C3)C4=C1C=CC(C#N)=C4.Cl
Biological Activity: BMS-191095 hydrochloride is a mitochondrial KATP channel opener. BMS-191095 hydrochloride can protect the myocardium without causing vasodilation or affecting electrophysiology, by prolonging the contraction time during ischemia, improving contractile function after reperfusion, and reducing lactate dehydrogenase (LDHM) release, thereby exerting its cardioprotective effects[1].
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BMS-191095 hydrochloride | BMS-191095 hydrochloride is a mitochondrial KATP channel opener. BMS-191095 hydrochloride can protect the myocardium without causing vasodilation or affecting electrophysiology, by prolonging the contraction time during ischemia, improving contractile function after reperfusion, and reducing lactate dehydrogenase (LDHM) release, thereby exerting its cardioprotective effects. | |||||||||||||||||||||
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Keywords
