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Cat. No.: HY-14257

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BMS-191095 hydrochloride

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

BMS-191095 hydrochloride is a mitochondrial K_ATP channel opener. BMS-191095 hydrochloride can protect the myocardium without causing vasodilation or affecting electrophysiology, by prolonging the contraction time during ischemia, improving contractile function after reperfusion, and reducing lactate dehydrogenase (LDHM) release, thereby exerting its cardioprotective effects.

For research use only. We do not sell to patients.

CAS No.: 166095-95-0
Formula: C₂₂H₂₂Cl₂N₄O₂
Molecular Weight:445.34

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

BMS-191095 hydrochloride Chemical Structure

CAS No.: 166095-95-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Chemical Information

CAS No. 166095-95-0
Molecular Weight 445.34
Formula C₂₂H₂₂Cl₂N₄O₂
SMILES

CC(O1)(C)[C@H](O)[C@@H](N(CC2=NC=CN2)C3=CC=C(Cl)C=C3)C4=C1C=CC(C#N)=C4.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Pharmaceuticals (Basel)

Pharmacological Profiling of KATP Channel Modulators: An Outlook for New Treatment Opportunities for Migraine. [Abstract]

2023 Feb 1;16(2):225. PMID: 37259373

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Grover GJ, et al. Pharmacologic profile of the selective mitochondrial-K(ATP) opener BMS-191095 for treatment of acute myocardial ischemia. Cardiovasc Drug Rev. 2002 Summer;20(2):121-36. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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BMS-191095 hydrochloride

1 Cited Publications

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BMS-191095 hydrochloride

Publications Citing Use of MedChemExpress (MCE) BMS-191095 hydrochloride

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Publications (1)

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BMS-191095 hydrochloride Related Classifications

HY-14257 Related Classifications