166734-83-4
166734-83-4
Chemical Structure
Ornidazole (Levo-)
Synonym(s): (S)-Ornidazole; Levornidazole
- CAS No.: 166734-83-4
- Formula:C7H10ClN3O3
- Molecular Weight:219.63
IUPAC Name: (S)-1-chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
InChIKey: IPWKIXLWTCNBKN-ZCFIWIBFSA-N
SMILES: CC1=NC=C([N+]([O-])=O)N1C[C@H](O)CCl
Biological Activity: Levo-ornidazole ((S)-Ornidazole) is the L-isomer of Ornidazole. Ornidazole (Levo-) increases GAD 65/67 expression and decreases brain Glu/GABA ratio. Ornidazole (Levo-) has a mild sedative effect. Levo-ornidazole can be used in the research of anti-anaerobic and anti-parasitic agents[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ornidazole (Levo-) | 98.86% | Levo-ornidazole ((S)-Ornidazole) is the L-isomer of Ornidazole. Ornidazole (Levo-) increases GAD 65/67 expression and decreases brain Glu/GABA ratio. Ornidazole (Levo-) has a mild sedative effect. Levo-ornidazole can be used in the research of anti-anaerobic and anti-parasitic agents. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-B0508ROrnidazole (Standard) -
Similarity Score 0.91
HY-121657ROrnidazole diol (Standard) -
Similarity Score 0.87
HY-B1118RSecnidazole (Standard) -
Similarity Score 0.84
HY-B0318RMetronidazole (Standard) -
Similarity Score 0.84
HY-B0318SMetronidazole-13C2,15N2 -
Similarity Score 0.83
HY-B0318AMetronidazole hydrochloride -
Similarity Score 0.82
HY-136436ATernidazole -
Similarity Score 0.82
HY-136436Ternidazole hydrochloride -
Similarity Score 0.80
HY-115249Metronidazole acetic acid -
Explore the MedChemAI to find more analogs
References
- [1]. Guo B, et al. Clinical Pharmacokinetics of Levornidazole in Elderly Subjects and Dosing Regimen Evaluation Using Pharmacokinetic/Pharmacodynamic Analysis. Clin Ther. 2017 Jul;39(7):1336-1346. [Content Brief]
- [2]. Wei TT, et al. Effects of the ornidazole enantiomers on the central nervous system: Involvement of the GABAA receptor. Chem Biol Interact. 2015 Dec 5;242:163-9. [Content Brief]
