167612-17-1
Chemical Structure
Terpendole I
- CAS No.: 167612-17-1
- Formula:C27H35NO5
- Molecular Weight:453.57
IUPAC Name: (2S,3R,3aR,4aS,4bS,6aS,12bS,12cR,14aS)-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-3,3a,5,6,6a,7,12,12b,12c,13,14,14a-dodecahydro-2H,4bH-oxireno[2'',3'':4',4a']chromeno[5',6':6,7]indeno[1,2-b]indole-3,4b-diol
InChIKey: AKOANWZRKXOJTC-ZWNZASDISA-N
SMILES: C[C@@]12[C@@]([H])(CC[C@]3([C@]45[C@]([H])(CC[C@@]32C)O[C@@H]([C@H]([C@H]4O5)O)C(O)(C)C)O)CC6=C1NC7=C6C=CC=C7
Biological Activity: Terpendole I is a fungal indole diterpenoid and an ACAT inhibitor (IC50 = 145 µM). Terpendole I can be used in studies related to lipid metabolism[1][2].
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Terpendole I | Terpendole I is a fungal indole diterpenoid and an ACAT inhibitor (IC50 = 145 µM). Terpendole I can be used in studies related to lipid metabolism. | |||||||||||||||||||||
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- [1]. Tomoda H, et al. Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. III. Production, isolation and structure elucidation of new components. J Antibiot (Tokyo). 1995;48(8):793-804. [Content Brief]
- [2]. Xu LL, et al. Prenylated Indole Diterpene Alkaloids from a Mine-Soil-Derived Tolypocladium sp. J Nat Prod. 2019;82(2):221-231. [Content Brief]
Keywords
