167648-73-9
Chemical Structure
SR-4554
- CAS No.: 167648-73-9
- Formula:C8H9F3N4O4
- Molecular Weight:282.18
IUPAC Name: 2-(2-nitro-1H-imidazol-1-yl)-N-(3,3,3-trifluoro-2-hydroxypropyl)acetamide
InChIKey: BTLNRJMECFTISR-UHFFFAOYSA-N
SMILES: O=C(NCC(O)C(F)(F)F)CN1C=CN=C1[N+]([O-])=O
Biological Activity: SR-4554 is a probe for the measurement of tumor hypoxia. SR-4554 undergoes enzymatic single-electron reduction reactions within hypoxic cells. SR-4554 determines the 19F retention index for four commonly used mouse tumors (EMT6, SCCVII, KILT and RIF-I) through 19F MRS technique. SR-4554 can used to detect tumor Hypoxia noninvasively by 19F magnetic resonance spectroscopy (19F MRS)[1].
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SR-4554 | 98.60% | SR-4554 is a probe for the measurement of tumor hypoxia. SR-4554 undergoes enzymatic single-electron reduction reactions within hypoxic cells. SR-4554 determines the 19F retention index for four commonly used mouse tumors (EMT6, SCCVII, KILT and RIF-I) through 19F MRS technique. SR-4554 can used to detect tumor Hypoxia noninvasively by 19F magnetic resonance spectroscopy (19F MRS). | ||||||||||||||||||||
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Keywords
