SR-4554
Based on 1 Customer Validation
SR-4554 is a probe for the measurement of tumor hypoxia. SR-4554 undergoes enzymatic single-electron reduction reactions within hypoxic cells. SR-4554 determines the 19F retention index for four commonly used mouse tumors (EMT6, SCCVII, KILT and RIF-I) through 19F MRS technique. SR-4554 can used to detect tumor Hypoxia noninvasively by 19F magnetic resonance spectroscopy (19F MRS).
For research use only. We do not sell to patients.
- Purity: 98.60%
- CAS No.: 167648-73-9
- Formula: C8H9F3N4O4
- Molecular Weight:282.18
-
Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
| Species | Dose | Route | Tmax | T1/2 | Clearance (CL) | Vd | AUC0-∞ |
|---|---|---|---|---|---|---|---|
| Mice[1] | 180 mg/kg | i.p. | 45 min | 51 min | 29 mL/min/kg | 1.8 L/kg | 0.36 μM·h |
Chemical Information
-
CAS No. 167648-73-9
-
Appearance Solid
-
Molecular Weight 282.18
-
Formula C8H9F3N4O4
-
Color White to off-white
-
SMILES
O=C(NCC(O)C(F)(F)F)CN1C=CN=C1[N+]([O-])=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (354.38 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5438 mL | 17.7192 mL | 35.4384 mL | 88.5959 mL |
| 5 mM | 0.7088 mL | 3.5438 mL | 7.0877 mL | 17.7192 mL | |
| 10 mM | 0.3544 mL | 1.7719 mL | 3.5438 mL | 8.8596 mL | |
| 15 mM | 0.2363 mL | 1.1813 mL | 2.3626 mL | 5.9064 mL | |
| 20 mM | 0.1772 mL | 0.8860 mL | 1.7719 mL | 4.4298 mL | |
| 25 mM | 0.1418 mL | 0.7088 mL | 1.4175 mL | 3.5438 mL | |
| 30 mM | 0.1181 mL | 0.5906 mL | 1.1813 mL | 2.9532 mL | |
| 40 mM | 0.0886 mL | 0.4430 mL | 0.8860 mL | 2.2149 mL | |
| 50 mM | 0.0709 mL | 0.3544 mL | 0.7088 mL | 1.7719 mL | |
| 60 mM | 0.0591 mL | 0.2953 mL | 0.5906 mL | 1.4766 mL | |
| 80 mM | 0.0443 mL | 0.2215 mL | 0.4430 mL | 1.1074 mL | |
| 100 mM | 0.0354 mL | 0.1772 mL | 0.3544 mL | 0.8860 mL |
SR-4554 Related Classifications
HY-116156 Related Classifications
Powered by Bioz