167933-78-0
Chemical Structure
SufS-IN-1
- CAS No.: 167933-78-0
- Formula:C6H9NO4
- Molecular Weight:159.14
IUPAC Name: (2R,3R)-3-(ethoxycarbonyl)aziridine-2-carboxylic acid
InChIKey: DIDDEKQOGOEWTH-QWWZWVQMSA-N
SMILES: O=C([C@]1([H])N[C@@]1([H])C(OCC)=O)O
Biological Activity: SufS-IN-1, a (2R,3R)-3-ethoxycarbonylaziridine-2-carboxylic acid (EAC), is a selective Cysteine desulfurase type II (SufS) inhibitor. SufS-IN-1 significantly inhibits the SufS activity by covalently binding to the cofactor PLP to form a stable PLP-ligand conjugates. SufS-IN-1 can be used for pathogenic microorganisms research, such as Plasmodium falciparum, Staphylococcus aureus and Mycobacterium tuberculosis[1].
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SufS-IN-1 | SufS-IN-1, a (2R,3R)-3-ethoxycarbonylaziridine-2-carboxylic acid (EAC), is a selective Cysteine desulfurase type II (SufS) inhibitor. SufS-IN-1 significantly inhibits the SufS activity by covalently binding to the cofactor PLP to form a stable PLP-ligand conjugates. SufS-IN-1 can be used for pathogenic microorganisms research, such as Plasmodium falciparum, Staphylococcus aureus and Mycobacterium tuberculosis. | |||||||||||||||||||||
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