167946-96-5
167946-96-5
Chemical Structure
Org 21465
- CAS No.: 167946-96-5
- Formula:C27H43NO4
- Molecular Weight:445.63
IUPAC Name: (2S,3S,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-2-(2,2-dimethylmorpholino)-3-hydroxy-10,13-dimethylhexadecahydro-11H-cyclopenta[a]phenanthren-11-one
InChIKey: HQEJMKVZYCQIIH-JJLPOIBOSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@H]([C@@H](N4CC(C)(OCC4)C)C2)O)([H])[C@@]5([H])[C@](CC3=O)([C@H](CC5)C(C)=O)C
Biological Activity: Org 21465 is an agent that can relieve pain. Org 21465 causes no cardiovascular or respiratory depression. Org 21465 can inhibit GABAA receptor in vivo[1][2].
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Org 21465 | Org 21465 is an agent that can relieve pain. Org 21465 causes no cardiovascular or respiratory depression. Org 21465 can inhibit GABAA receptor in vivo. | |||||||||||||||||||||
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References
- [1]. Vanlersberghe C, et, al. Etomidate and other non-barbiturates. Handb Exp Pharmacol. 2008:(182):267-82. [Content Brief]
- [2]. Visser SAG, et, al. Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo. J Pharmacol Exp Ther. 2002 Nov;303(2):616-26. [Content Brief]
Keywords
