1680205-79-1
Chemical Structure
ELA-32(human)
- CAS No.: 1680205-79-1
- Formula:C170H289N63O39S4
- Molecular Weight:3967.82
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: O=C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCSC)C(N3[C@@H](CCC3)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N5[C@@H](CCC5)C(N[C@@H](CC6=CC=CC=C6)C(N7[C@@H](CCC7)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC8=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H]8CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(N)=O)N
Biological Activity: ELA-32 (human) is a potent critical cardiac developmental peptide that acts through the G-protein–coupled apelin receptor[1].
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ELA-32(human) | ELA-32 (human) is a potent critical cardiac developmental peptide that acts through the G-protein–coupled apelin receptor. | |||||||||||||||||||||
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- [1]. Yang P, et al. Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension. Circulation. 2017;135(12):1160-1173. [Content Brief]
Keywords