1693735-07-7
1693735-07-7
Chemical Structure
HSF1 ligand-1
- CAS No.: 1693735-07-7
- Formula:C26H20ClN3O4
- Molecular Weight:473.91
InChIKey: ZKWHTQDLPXXXDP-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2N=C(C)C=CC2=C1)NC3=CC(NC(C4=CC=C(OCCO5)C5=C4)=O)=CC=C3Cl
Biological Activity: HSF1 ligand-1 (compound 18) is a ligand for heat shock transcription factor HSF1, as well as a binder for the high-affinity nuclear protein pirin, with an SPR Kd of 44 nM. HSF1 ligand-1 can be used to prepare HSF1-targeted PROTAC degrader (HY-122653)[1].
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HSF1 ligand-1 | HSF1 ligand-1 (compound 18) is a ligand for heat shock transcription factor HSF1, as well as a binder for the high-affinity nuclear protein pirin, with an SPR Kd of 44 nM. HSF1 ligand-1 can be used to prepare HSF1-targeted PROTAC degrader (HY-122653). | |||||||||||||||||||||
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