1702816-75-8
1702816-75-8
Chemical Structure
Linperlisib
Synonym(s): YY-20394
- CAS. Nr.: 1702816-75-8
- Formula:C28H37FN6O5S
- Molecular Weight:588.69
IUPAC Name: N-(5-(6-fluoro-8-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-2-morpholinoquinazolin-4-yl)-2-methoxypyridin-3-yl)methanesulfonamide
InChIKey: NVWKNQGHVMMAJW-UHFFFAOYSA-N
SMILES: CS(=O)(NC1=CC(C2=C3C=C(F)C=C(CN4CCC(C(C)(O)C)CC4)C3=NC(N5CCOCC5)=N2)=CN=C1OC)=O
Biological Activity: Linperlisib (YY-20394) is a potent, orally bioavailable and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC50 of 6.4 nM[1].
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Linperlisib | 98.83% | Linperlisib (YY-20394) is a potent, orally bioavailable and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC50 of 6.4 nM. | ||||||||||||||||||||
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