170632-41-4
Chemical Structure
YD-3
- CAS No.: 170632-41-4
- Formula:C23H20N2O2
- Molecular Weight:356.42
IUPAC Name: ethyl 4-(1-benzyl-1H-indazol-3-yl)benzoate
InChIKey: LPROLPQTWKDPNU-UHFFFAOYSA-N
SMILES: O=C(OCC)C1=CC=C(C2=NN(CC3=CC=CC=C3)C4=C2C=CC=C4)C=C1
Biological Activity: YD-3 is a platelet activation inhibitor. YD-3 inhibits Thrombine-induced rabbit platelets aggregation (IC50: 28.3 μM) and phosphoinositol production. In addition, YD-3 also inhibits Trypsin-induced platelet aggregation in human and rabbit with the IC50 of 38.1 μM and 5.7 μM, respectively, but does not affect the proteolytic activity of trypsin[1].
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YD-3 | YD-3 is a platelet activation inhibitor. YD-3 inhibits Thrombine-induced rabbit platelets aggregation (IC50: 28.3 μM) and phosphoinositol production. In addition, YD-3 also inhibits Trypsin-induced platelet aggregation in human and rabbit with the IC50 of 38.1 μM and 5.7 μM, respectively, but does not affect the proteolytic activity of trypsin. | |||||||||||||||||||||
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Keywords
