17375-41-6
Chemical Structure
Iron(II) sulfate hydrate
- CAS No.: 17375-41-6
- Formula:FeH2O5S
- Molecular Weight:169.92
IUPAC Name: sulfuric acid, iron salt hydrate
InChIKey: YXIKXINTNAICKH-UHFFFAOYSA-N
SMILES: O=S(=O)=[Fe](=O)=O.O
Biological Activity: Iron(II) sulfate hydrate is an iron(II) salt with oral activity, acting as an iron supplier, and is easily oxidized to iron(III) in water. Iron(II) sulfate hydrate induces apoptotic morphological changes in cancer cells, and promotes dose‑dependent iron accumulation in rats. Iron(II) sulfate hydrate can be used in studies of leukemia, breast cancer, iron deficiency, anemia, and restless legs syndrome[1][2][3].
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Iron(II) sulfate hydrate | Iron(II) sulfate hydrate is an iron(II) salt with oral activity, acting as an iron supplier, and is easily oxidized to iron(III) in water. Iron(II) sulfate hydrate induces apoptotic morphological changes in cancer cells, and promotes dose‑dependent iron accumulation in rats. Iron(II) sulfate hydrate can be used in studies of leukemia, breast cancer, iron deficiency, anemia, and restless legs syndrome. | |||||||||||||||||||||
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- [1]. Kok SH, et al. Paradoxical proliferative potential of iron (II) sulphate on cancer cells after the 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay. Int J Mol Med. 2007 Jun;19(6):971-5.
- [2]. Appel MJ, et al. Disposition, accumulation and toxicity of iron fed as iron (II) sulfate or as sodium iron EDTA in rats. Food Chem Toxicol. 2001;39(3):261-269. [Content Brief]
- [3]. Auerbach M, et al. Iron Deficiency in Adults: A Review. JAMA. 2025 May 27;333(20):1813-1823. [Content Brief]
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