174262-13-6
174262-13-6
Chemical Structure
SDZ285428
- CAS No.: 174262-13-6
- Formula:C24H20ClN3O
- Molecular Weight:401.89
IUPAC Name: N-(2-(1H-imidazol-1-yl)-2-phenylethyl)-4'-chloro-[1,1'-biphenyl]-4-carboxamide
InChIKey: FHHNSSGZEIVGMS-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=CC=C(Cl)C=C2)C=C1)NCC(N3C=CN=C3)C4=CC=CC=C4
Biological Activity: SDZ285428 is a CYP51 inhibitor. SDZ285428 inhibits Trypanosoma cruzi (TC) CYP51 with I/E2 <1 (5 min) and I/E2=9 (1 h). SDZ285428 inhibits Trypanosoma brucei (TB) CYP51 with I/E2 <1 (5 min) and I/E2=35 (1 h)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SDZ285428 | 98.00% | SDZ285428 is a CYP51 inhibitor. SDZ285428 inhibits Trypanosoma cruzi (TC) CYP51 with I/E2 <1 (5 min) and I/E2=9 (1 h). SDZ285428 inhibits Trypanosoma brucei (TB) CYP51 with I/E2 <1 (5 min) and I/E2=35 (1 h). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-113907SDZ-285604 -
Similarity Score 0.60
HY-B0301Bifonazole -
Similarity Score 0.59
HY-10661FL104 -
Similarity Score 0.59
HY-118843Lombazole -
Similarity Score 0.55
HY-115713Heme Oxygenase-1-IN-2 -
Similarity Score 0.54
![N4,N4'-Di(pyridin-4-yl)-[1,1'-biphenyl]-4,4'-dicarboxamide Chemical Structure](//file.medchemexpress.com/product_pic/hy-w243985.gif)
HY-W243985N4,N4'-Di(pyridin-4-yl)-[1,1'-biphenyl]-4,4'-dicarboxamide -
Similarity Score 0.54
HY-W8560334,4'-Bis((1H-imidazol-1-yl)methyl)-1,1'-biphenyl -
Similarity Score 0.54
HY-144755MC2652 -
Similarity Score 0.53
HY-130752VNI -
Explore the MedChemAI to find more analogs
![N4,N4'-Di(pyridin-4-yl)-[1,1'-biphenyl]-4,4'-dicarboxamide Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w243985.gif)
