175796-45-9
175796-45-9
Chemical Structure
ISP-VT
Synonym(s): Isopropyl vanillate
- CAS No.: 175796-45-9
- Formula:C11H14O4
- Molecular Weight:210.23
InChIKey: LLBXZZOFEUAEOM-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C(OC)=C1)O)OC(C)C
Biological Activity: ISP-VT (Isopropyl vanillate) is a COX-2 inhibitor. ISP-VT exhibits anti-inflammatory, antipyretic and immunomodulatory activities. ISP-VT reduces neutrophil migration and the release of inflammatory factors. ISP-VT can be used for the research of inflammatory and immune diseases and other conditions[1][2].
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ISP-VT | ISP-VT (Isopropyl vanillate) is a COX-2 inhibitor. ISP-VT exhibits anti-inflammatory, antipyretic and immunomodulatory activities. ISP-VT reduces neutrophil migration and the release of inflammatory factors. ISP-VT can be used for the research of inflammatory and immune diseases and other conditions. | |||||||||||||||||||||
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References
- [1]. Ishimata N, et al. Structure-activity relationships of vanillic acid ester analogs in inhibitory effect of antigen-mediated degranulation in rat basophilic leukemia RBL-2H3 cells. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3533-6. [Content Brief]
- [2]. Nogueira KM, et al. Efficacy of a phenol derivative, isopropyl vanillate, as an anti-inflammatory agent: A new small molecule inhibitor of COX and neutrophil migration. Drug Dev Res. 2019;80(5):666-679. [Content Brief]
Keywords
