176957-55-4
176957-55-4
Chemical Structure
CCT007093
- CAS No.: 176957-55-4
- Formula:C15H12OS2
- Molecular Weight:272.39
IUPAC Name: (2E,5E)-2,5-bis(thiophen-2-ylmethylene)cyclopentan-1-one
InChIKey: KPFZCKDPBMGECB-WGDLNXRISA-N
SMILES: O=C1/C(CC/C1=C\C2=CC=CS2)=C/C3=CC=CS3
Biological Activity: CCT007093 is an effective protein phosphatase 1D (PPM1D Wip1) inhibitor. Wip1 inhibition can activate the mTORC1 pathway and enhance hepatocyte proliferation after hepatectomy[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CCT007093 | 98.34% | CCT007093 is an effective protein phosphatase 1D (PPM1D Wip1) inhibitor. Wip1 inhibition can activate the mTORC1 pathway and enhance hepatocyte proliferation after hepatectomy. | ||||||||||||||||||||
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References
- [1]. Lingling Zhang, et al. Inhibition of wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mammalian target of rapamycin. Hepatology. 2015 Jun;61(6):2030-41. [Content Brief]
- [2]. S Rayter, et al. A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. Oncogene. 2008 Feb 14;27(8):1036-44. [Content Brief]
Keywords
