1780303-76-5
1780303-76-5
Chemical Structure
DDR1-IN-1 dihydrochloride
- CAS No.: 1780303-76-5
- Formula:C30H33Cl2F3N4O3
- Molecular Weight:625.51
IUPAC Name: 4-((4-ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-((2-oxoindolin-5-yl)oxy)phenyl)-3-(trifluoromethyl)benzamide dihydrochloride
InChIKey: PBUOJKYQZINPKD-UHFFFAOYSA-N
SMILES: CC1=C(C=C(C=C1)NC(C2=CC=C(C(C(F)(F)F)=C2)CN3CCN(CC3)CC)=O)OC4=CC(C5)=C(C=C4)NC5=O.Cl.Cl
Biological Activity: DDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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DDR1-IN-1 dihydrochloride | 98.92% | DDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM). | ||||||||||||||||||||
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