1781233-72-4
Chemical Structure
(Rac)-PAT-494
- CAS No.: 1781233-72-4
- Formula:C20H16FN3O2
- Molecular Weight:349.36
IUPAC Name: 6-(4-fluorobenzyl)-5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione
InChIKey: LRGAZQBFSHLAGN-UHFFFAOYSA-N
SMILES: FC1=CC=C(CN2C3=CC=CC=C3C4=C2CN(C5C4)C(NC5=O)=O)C=C1
Biological Activity: (Rac)-PAT-494 is a type II autotaxin inhibitor with the activity of inhibiting the production of lysophosphatidic acid (LPA) in the blood. (Rac)-PAT-494 can participate in the inhibition of diseases related to cancer, fibrosis and inflammation by antagonizing the function of autotaxin. (Rac)-PAT-494 shows high activity in biochemical and plasma tests. (Rac)-PAT-494 can reduce plasma LPA levels after oral administration to rats[1].
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(Rac)-PAT-494 | (Rac)-PAT-494 is a type II autotaxin inhibitor with the activity of inhibiting the production of lysophosphatidic acid (LPA) in the blood. (Rac)-PAT-494 can participate in the inhibition of diseases related to cancer, fibrosis and inflammation by antagonizing the function of autotaxin. (Rac)-PAT-494 shows high activity in biochemical and plasma tests. (Rac)-PAT-494 can reduce plasma LPA levels after oral administration to rats. | |||||||||||||||||||||
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