178273-87-5
178273-87-5
Chemical Structure
Piboserod hydrochloride
Synonym(s): SB-207266 hydrochloride
- CAS No.: 178273-87-5
- Formula:C22H32ClN3O2
- Molecular Weight:405.96
IUPAC Name: N-((1-butylpiperidin-4-yl)methyl)-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide hydrochloride
InChIKey: UABVCZHWRUGYSR-UHFFFAOYSA-N
SMILES: [H]Cl.O=C(C1=C(OCCC2)N2C3=C1C=CC=C3)NCC4CCN(CCCC)CC4
Biological Activity:
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Piboserod hydrochloride | Piboserod (SB 207266) Hcl is a selective 5-HT(4) receptor antagonist. | |||||||||||||||||||||
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References
- Darblade B, et al. Piboserod (SB 207266), a selective 5-HT4 receptor antagonist, reduces serotonin potentiation of neurally-mediated contractile responses of human detrusor muscle. World J Urol. 2005 Jun;23(2):147-51. [Content Brief]
- Kjekshus JK, et al. Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular function in patients with symptomatic heart failure. Eur J Heart Fail. 2009 Aug;11(8):771-8. [Content Brief]
- Nirogi R, et al. In-vivo rat striatal 5-HT4 receptor occupancy using non-radiolabelled SB207145. J Pharm Pharmacol. 2013 May;65(5):704-12. [Content Brief]
Keywords
