1809050-49-4
1809050-49-4
Chemical Structure
KAR425
- CAS No.: 1809050-49-4
- Formula:C19H27N3
- Molecular Weight:297.44
IUPAC Name: (E)-N-((3'-ethyl-4'-methyl-1H,5'H-[2,2'-bipyrrol]-5'-ylidene)methyl)cycloheptanamine
InChIKey: UMOKUEQLTLBMFK-QGOAFFKASA-N
SMILES: CCC1=C(C)/C(N=C1C2=CC=CN2)=C\NC3CCCCCC3
Biological Activity: KAR425 is a potent and orally active antimalarial agent. KAR425 shows antimalarial activity against the Chloroquine-sensitive (CQS) D6, the Chloroquine-resistant (CQR) Dd2, and 7G8 strains of Plasmodium falciparum, with IC50 values of 62 nM, 55 nM, and 60 nM, respectively[1].
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KAR425 | KAR425 is a potent and orally active antimalarial agent. KAR425 shows antimalarial activity against the Chloroquine-sensitive (CQS) D6, the Chloroquine-resistant (CQR) Dd2, and 7G8 strains of Plasmodium falciparum, with IC50 values of 62 nM, 55 nM, and 60 nM, respectively. | |||||||||||||||||||||
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