18110-87-7
18110-87-7
Chemical Structure
4,5-Dimethoxycanthin-6-one
- CAS No.: 18110-87-7
- Formula:C16H12N2O3
- Molecular Weight:280.28
IUPAC Name: 4,5-dimethoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
InChIKey: ATONBUGCNDSBBC-UHFFFAOYSA-N
SMILES: O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C(OC)=C1OC
Biological Activity: 4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2-mediated phenacetin O-deethylation with an IC50 value of 1.7μM and a Ki value of 2.6 μM. 4,5-Dimethoxycanthin-6-one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4,5-Dimethoxycanthin-6-one | 98.68% | 4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2-mediated phenacetin O-deethylation with an IC50 value of 1.7μM and a Ki value of 2.6 μM. 4,5-Dimethoxycanthin-6-one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae). | ||||||||||||||||||||
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References
Keywords
