182133-25-1
Chemical Structure
Arzoxifene
Synonym(s): LY353381; SERM III
- CAS No.: 182133-25-1
- Formula:C28H29NO4S
- Molecular Weight:475.60
IUPAC Name: 2-(4-methoxyphenyl)-3-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)benzo[b]thiophen-6-ol
InChIKey: MCGDSOGUHLTADD-UHFFFAOYSA-N
SMILES: OC1=CC=C(C(OC2=CC=C(OCCN3CCCCC3)C=C2)=C(C4=CC=C(OC)C=C4)S5)C5=C1
Biological Activity: Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator with a fixed ring structure similar to raloxifene. Arzoxifene has minimal side effects with powerful antiestrogenic effects on breast cancer and endometrium, with equally strong favorable estrogenic effects on bone and lipid profile[1].
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Arzoxifene | Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator with a fixed ring structure similar to raloxifene. Arzoxifene has minimal side effects with powerful antiestrogenic effects on breast cancer and endometrium, with equally strong favorable estrogenic effects on bone and lipid profile. | |||||||||||||||||||||
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Keywords
