18430-06-3
18430-06-3
Chemical Structure
N-Acetyl serotonin β-D-glucuronide
- CAS No.: 18430-06-3
- Formula:C18H22N2O8
- Molecular Weight:394.38
InChIKey: DRKQFNYKSNWOTC-RNGZQALNSA-N
SMILES: CC(NCCC(C1=C2)=CNC1=CC=C2O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O)=O
Biological Activity: N-Acetyl serotonin β-D-glucuronide is a glucuronidated metabolite of N-acetylserotonin (HY-107854) and a probe metabolite for UGT1A6 activity assays.N-Acetyl serotonin β-D-glucuronide forms from N-acetyl serotonin via glucuronidation catalyzed by a UGT enzyme[1][2].
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N-Acetyl serotonin β-D-glucuronide | N-Acetyl serotonin β-D-glucuronide is a glucuronidated metabolite of N-acetylserotonin (HY-107854) and a probe metabolite for UGT1A6 activity assays.N-Acetyl serotonin β-D-glucuronide forms from N-acetyl serotonin via glucuronidation catalyzed by a UGT enzyme. | |||||||||||||||||||||
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References
- [1]. Heo JK, et al. Inhibitory Effect of Selaginellins from Selaginella tamariscina (Beauv.) Spring against Cytochrome P450 and Uridine 5'-Diphosphoglucuronosyltransferase Isoforms on Human Liver Microsomes. Molecules. 2017;22(10):1590. Published 2017 Sep 21. [Content Brief]
- [2]. Liu S, et al. The regulatory roles of pparα on hepatic drug-metabolizing enzymes in primary sclerosing cholangitis Syrian hamsters. Biochem Pharmacol. 2025;242(Pt 2):117339. [Content Brief]
Keywords
