1852451-96-7
Chemical Structure
AMPK activator 8
- CAS No.: 1852451-96-7
- Formula:C25H21ClN2O6
- Molecular Weight:480.90
IUPAC Name: 4'-(5-chloro-2-(((3R,3aR,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl)oxy)-1H-benzo[d]imidazol-6-yl)-[1,1'-biphenyl]-2,6-diol
InChIKey: MMOYHXCYJWHUCI-LUGTWXOSSA-N
SMILES: ClC1=C(C2=CC=C(C3=C(C=CC=C3O)O)C=C2)C=C4NC(O[C@H]5[C@]6([H])[C@]([C@@H](CO6)O)([H])OC5)=NC4=C1
Biological Activity: AMPK activator 8 (compound 2) is an AMP-activated protein kinase (AMPK) activator with EC50s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively. AMPK activator 8 can be used for the research of type 2 diabetes[1].
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AMPK activator 8 | AMPK activator 8 (compound 2) is an AMP-activated protein kinase (AMPK) activator with EC50s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively. AMPK activator 8 can be used for the research of type 2 diabetes. | |||||||||||||||||||||
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