186205-37-8
Chemical Structure
Cy2 (iodine)
Synonym(s): Cyanine2 (iodine)
- CAS No.: 186205-37-8
- Formula:C25H27IN2O4
- Molecular Weight:546.40
IUPAC Name: 3-(5-carboxypentyl)-2-((1E,3Z)-3-(3-ethylbenzo[d]oxazol-2(3H)-ylidene)prop-1-en-1-yl)benzo[d]oxazol-3-ium iodide
InChIKey: WGEKKSZOJOJNAZ-UHFFFAOYSA-N
SMILES: O=C(O)CCCCC[N+](C(C=CC=C1)=C1O2)=C2/C=C/C=C3OC(C=CC=C4)=C4N\3CC.[I-]
Biological Activity: Cy2 iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2].
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Cy2 (iodine) | 96.81% | Cy2 iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance. | ||||||||||||||||||||
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- [1]. Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108. [Content Brief]
- [2]. Sandberg A, et al. Use of Time-Resolved Fluorescence To Improve Sensitivity and Dynamic Range of Gel-Based Proteomics. Anal Chem. 2016 Mar 15;88(6):3067-74. [Content Brief]
Keywords
