186611-55-2
186611-55-2
Chemical Structure
SU-4313
- CAS. Nr.: 186611-55-2
- Formula:C18H17NO
- Molecular Weight:263.33
IUPAC Name: (Z)-3-(4-isopropylbenzylidene)indolin-2-one
InChIKey: IRQQWCZKCUQNSO-WJDWOHSUSA-N
SMILES: O=C1NC2=C(/C1=C/C3=CC=C(C(C)C)C=C3)C=CC=C2
Biological Activity: SU-4313 is a potent protein tyrosine kinases (PTKs) modulator with IC50s of 14.5 μM, 18.8 μM, 11 μM, 16.9 μM, 8.0 μM for PDGFR, FLK-1, EGFR, HER2 Kinase and IGF-1R, respectively. SU-4313 has the potential for modulating tyrosine kinase signal transduction in order to regulate abnormal cell proliferation[1].
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SU-4313 | 99.31% | SU-4313 is a potent protein tyrosine kinases (PTKs) modulator with IC50s of 14.5 μM, 18.8 μM, 11 μM, 16.9 μM, 8.0 μM for PDGFR, FLK-1, EGFR, HER2 Kinase and IGF-1R, respectively. SU-4313 has the potential for modulating tyrosine kinase signal transduction in order to regulate abnormal cell proliferation. | ||||||||||||||||||||
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