186835-06-3
Chemical Structure
F050
- CAS No.: 186835-06-3
- Formula:C21H20O
- Molecular Weight:288.38
InChIKey: RWGNIRFXQDNZLG-UHFFFAOYSA-N
SMILES: OCCCC1=CC(C2=CC=CC=C2)=C(C3=CC=CC=C3)C=C1
Biological Activity: F050 is an orally active intracellular platelet calcium ([Ca2+]i) inhibitor. F050 inhibits thrombin-induced elevation of intracellular calcium in platelets. F050 inhibits platelet aggregation induced by CaCl2, arachidonic acid, collagen, adenosine diphosphate (ADP), and thrombin across multiple species, and reduces thrombus formation in an extracorporeal circulation thrombosis model in guinea pigs. F050 also inhibits hypotonic NaCl-induced erythrocyte hemolysis and is used in research on thrombotic diseases[1].
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F050 | F050 is an orally active intracellular platelet calcium ([Ca2+]i) inhibitor. F050 inhibits thrombin-induced elevation of intracellular calcium in platelets. F050 inhibits platelet aggregation induced by CaCl2, arachidonic acid, collagen, adenosine diphosphate (ADP), and thrombin across multiple species, and reduces thrombus formation in an extracorporeal circulation thrombosis model in guinea pigs. F050 also inhibits hypotonic NaCl-induced erythrocyte hemolysis and is used in research on thrombotic diseases. | |||||||||||||||||||||
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