187269-60-9
Chemical Structure
Bimosiamose disodium
Synonym(s): TBC-1269Z
- CAS No.: 187269-60-9
- Formula:C46H52Na2O16
- Molecular Weight:906.88
IUPAC Name: sodium 2,2'-(hexane-1,6-diylbis(6'-(((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-[1,1'-biphenyl]-3',3-diyl))diacetate
InChIKey: ZGEPTUZKSXWWAB-PNGDFCJYSA-L
SMILES: OC[C@H]([C@@H](O)[C@H](O)[C@@H]1O)O[C@@H]1OC(C=C2)=C(C3=CC(CC(O[Na])=O)=CC=C3)C=C2CCCCCCC(C=C4)=CC(C5=CC(CC(O[Na])=O)=CC=C5)=C4O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@@H]6O)CO
Biological Activity: Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose disodium has anti-inflammatory effects[1].
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Bimosiamose disodium | Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose disodium has anti-inflammatory effects. | |||||||||||||||||||||
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Keywords
