187793-52-8
187793-52-8
Chemical Structure
T-2513 hydrochloride
- CAS No.: 187793-52-8
- Formula:C25H28ClN3O5
- Molecular Weight:485.96
IUPAC Name: (S)-9-(3-aminopropoxy)-4,11-diethyl-4-hydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione hydrochloride
InChIKey: MIZGPLODSZKVPX-UQIIZPHYSA-N
SMILES: CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(OCCCN)C=C51.Cl
Biological Activity: T-2513 hydrochloride is a selective topoisomerase I inhibitor. T-2513 hydrochloride binds covalently to and stabilizes the topoisomerase I-DNA complex and inhibits DNA replication and RNA synthesis, ultimately leading to cell death[1].
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T-2513 hydrochloride | T-2513 hydrochloride is a selective topoisomerase I inhibitor. T-2513 hydrochloride binds covalently to and stabilizes the topoisomerase I-DNA complex and inhibits DNA replication and RNA synthesis, ultimately leading to cell death. | |||||||||||||||||||||
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