188106-83-4
188106-83-4
Chemical Structure
NU 1085
- CAS No.: 188106-83-4
- Formula:C14H11N3O2
- Molecular Weight:253.26
IUPAC Name: 2-(4-hydroxyphenyl)-1H-benzo[d]imidazole-4-carboxamide
InChIKey: KOUGHMOSYJCJLE-UHFFFAOYSA-N
SMILES: NC(C1=C2C(NC(C3=CC=C(O)C=C3)=N2)=CC=C1)=O
Biological Activity: NU 1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor with a Ki of 6 nM. NU 1085 shows strong cytotoxicity to cancer cells (LC50 = 83-94 μM) and can enhance the anticancer effect of Temozolomide (HY-17364). NU 1085 can be used for the research of cancer, such as lung cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
NU 1085 | NU 1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor with a Ki of 6 nM. NU 1085 shows strong cytotoxicity to cancer cells (LC50 = 83-94 μM) and can enhance the anticancer effect of Temozolomide (HY-17364). NU 1085 can be used for the research of cancer, such as lung cancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
