188259-69-0
Chemical Structure
4-Hydroxy valsartan
Synonym(s): Valeryl-4-hydroxyvalsartan; CGP 71580
- CAS No.: 188259-69-0
- Formula:C24H29N5O4
- Molecular Weight:451.52
IUPAC Name: N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-(4-hydroxypentanoyl)-L-valine
InChIKey: ICSQZMPILLPFKC-XLDIYJRPSA-N
SMILES: O=C(N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NN=NN3)[C@@H](C(C)C)C(O)=O)CCC(C)O
Biological Activity: 4-Hydroxy valsartan is a metabolite of Valsartan (HY-18204). 4-Hydroxy valsartan regulates the expression of platelet surface receptors and inhibits conventional plasma or whole blood collagen induced platelet aggregation. 4-Hydroxy valsartan has antiplatelet activity[1].
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4-Hydroxy valsartan | 4-Hydroxy valsartan is a metabolite of Valsartan (HY-18204). 4-Hydroxy valsartan regulates the expression of platelet surface receptors and inhibits conventional plasma or whole blood collagen induced platelet aggregation. 4-Hydroxy valsartan has antiplatelet activity. | |||||||||||||||||||||
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Keywords