1885-29-6
1885-29-6
Chemical Structure
2-Aminobenzonitrile
- CAS No.: 1885-29-6
- Formula:C7H6N2
- Molecular Weight:118.14
IUPAC Name: 2-aminobenzonitrile
InChIKey: HLCPWBZNUKCSBN-UHFFFAOYSA-N
SMILES: N#CC1=C(N)C=CC=C1
Biological Activity: 2-Aminobenzonitrile is an aminobenzonitrile synthetic building block and an arylamine coupling ligand. 2-Aminobenzonitrile participates in the Friedländer condensation reaction. 2-Aminobenzonitrile is an o-cyanoaniline precursor that can be used to synthesize cyclic N-linked C8,N7-dG adducts. 2-Aminobenzonitrile is used to prepare Tacrine (HY-111338) and its analogs[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Aminobenzonitrile | 99.96% | 2-Aminobenzonitrile is an aminobenzonitrile synthetic building block and an arylamine coupling ligand. 2-Aminobenzonitrile participates in the Friedländer condensation reaction. 2-Aminobenzonitrile is an o-cyanoaniline precursor that can be used to synthesize cyclic N-linked C8,N7-dG adducts. 2-Aminobenzonitrile is used to prepare Tacrine (HY-111338) and its analogs. | ||||||||||||||||||||
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References
- [1]. Camps P, et al. Tacrine-huperzine A hybrids (huprines): a new class of highly potent and selective acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease. Mini reviews in medicinal chemistry. 2001 Jul;1(2):163-74. [Content Brief]
- [2]. Useini L, et al. Carboranyl Analogues of Mefenamic Acid and Their Biological Evaluation. ACS omega. 2022 Jul 19;7(28):24282-24291. [Content Brief]
- [3]. Manning TW, et al. Structure of an unusual tetracyclic deoxyguanosine adduct: implications for frameshift mutagenicity of ortho-cyano nitroanilines. Chemical Research in Toxicology. 2020 Feb 17;33(2):584-93. [Content Brief]
- [4]. Kulkarni AS, et al. Silicon incorporated tacrine: design, synthesis, and evaluation of biological and pharmacokinetic parameters. RSC medicinal chemistry. 2025 Jun 18;16(6):2603-2614. [Content Brief]
