1888328-89-9
1888328-89-9
Chemical Structure
EPZ0025654
Synonym(s): GSK3536023
- CAS No.: 1888328-89-9
- Formula:C29H33ClN8O3
- Molecular Weight:577.08
IUPAC Name: (R)-1-(3-(4-(2-(azetidin-1-yl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)-6-(3,5-dimethylisoxazol-4-yl)-5-methylpyrimidin-2-yl)-4-chlorophenoxy)-3-(methylamino)propan-2-ol
InChIKey: FJRSBGGFLPVXPH-HXUWFJFHSA-N
SMILES: O[C@H](CNC)COC1=CC=C(Cl)C(C2=NC(C3=C(C)ON=C3C)=C(C)C(N4CC5=NC(N6CCC6)=NC=C5C4)=N2)=C1
Biological Activity: EPZ0025654 (GSK3536023) is an inhibitor for protein arginine methyltransferases 4 (PRMT4) (which is also known as coactivator associated arginine methyltransferase 1 CARM1), with IC50 of 3 nM[1].
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EPZ0025654 | EPZ0025654 (GSK3536023) is an inhibitor for protein arginine methyltransferases 4 (PRMT4) (which is also known as coactivator associated arginine methyltransferase 1 CARM1), with IC50 of 3 nM. | |||||||||||||||||||||
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