1907679-70-2
Chemical Structure
Aurora kinase ligand-1
- CAS No.: 1907679-70-2
- Formula:C24H26FN7O3
- Molecular Weight:479.51
IUPAC Name: N-(3-fluorophenyl)-2-(3-((7-(3-((2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)acetamide
InChIKey: SDZUCENMNALQOM-UHFFFAOYSA-N
SMILES: OCCNCCCOC1=CC2=NC=NC(NC3=NNC(CC(NC4=CC=CC(F)=C4)=O)=C3)=C2C=C1
Biological Activity: Aurora kinase ligand-1 (Compound I-4) is an Aurora kinase B (AURKB) PROTAC ligand. Aurora kinase ligand-1 can be conjugated with E3 ligase Ligand (HY-112078) and linker to synthesize AURKB PROTAC degrader MS44 (HY-175525). MS44 can be used for cancer research[1].
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Aurora kinase ligand-1 | Aurora kinase ligand-1 (Compound I-4) is an Aurora kinase B (AURKB) PROTAC ligand. Aurora kinase ligand-1 can be conjugated with E3 ligase Ligand (HY-112078) and linker to synthesize AURKB PROTAC degrader MS44 (HY-175525). MS44 can be used for cancer research. | |||||||||||||||||||||
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Keywords
