191219-80-4
191219-80-4
Chemical Structure
YM976
- CAS No.: 191219-80-4
- Formula:C17H16ClN3O
- Molecular Weight:313.78
IUPAC Name: 4-(3-chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
InChIKey: MNHXYNNKDDXKNP-UHFFFAOYSA-N
SMILES: O=C1N(CC)C2=NC(CC)=CC=C2C(C3=CC=CC(Cl)=C3)=N1
Biological Activity: YM976 is a phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.2 nM. YM976 shows the dissociation of anti-inflammatory activities from emetic effects and inhibits the antigen-induced airway responses[1].
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YM976 | 99.0% | YM976 is a phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.2 nM. YM976 shows the dissociation of anti-inflammatory activities from emetic effects and inhibits the antigen-induced airway responses. | ||||||||||||||||||||
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References
Keywords
