1914136-10-9
1914136-10-9
Chemical Structure
DA-1241
- CAS No.: 1914136-10-9
- Formula:C25H31F2N5O2
- Molecular Weight:471.54
InChIKey: XQSZLXRXPGLHLH-UHFFFAOYSA-N
SMILES: CC(C1=NC(C2=C(F)C=C(OCCCC3CCN(C4=NC=C(CC)C=N4)CC3)C=C2F)=NO1)C
Biological Activity: DA-1241 is a GPR119 agonist. DA-1241 reduces macrophage differentiation through downregulation of NFκB signaling by activating GPR119. DA-1241, alone and in combination with a DPP4 inhibitor, reduces liver inflammation and restores inflammation-related liver gene expression. DA-1241 can be used for the research of metabolic dysfunction-associated steatohepatitis (MASH)[1].
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DA-1241 | 99.18% | DA-1241 is a GPR119 agonist. DA-1241 reduces macrophage differentiation through downregulation of NFκB signaling by activating GPR119. DA-1241, alone and in combination with a DPP4 inhibitor, reduces liver inflammation and restores inflammation-related liver gene expression. DA-1241 can be used for the research of metabolic dysfunction-associated steatohepatitis (MASH). | ||||||||||||||||||||
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References
Keywords
