1914944-54-9
1914944-54-9
Chemical Structure
ROMK-IN-32
- CAS No.: 1914944-54-9
- Formula:C24H28N4O5
- Molecular Weight:452.50
IUPAC Name: (R)-8-(2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydroisobenzofuran-5-yl)ethyl)-2-(1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)-2,8-diazaspiro[4.5]decan-1-one
InChIKey: AEQJLXICIKRMCT-IBGZPJMESA-N
SMILES: O=C1N(C(C=C2)=NN(C)C2=O)CCC13CCN(C[C@@H](C4=C(C)C5=C(C(OC5)=O)C=C4)O)CC3
Biological Activity: ROMK-IN-32 is a renal outer medullary potassium channel (ROMK) inhibitor with an IC50 of 35 nM. ROMK-IN-32 also inhibits hERG with an IC50 of 22 μM[1].
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ROMK-IN-32 | ROMK-IN-32 is a renal outer medullary potassium channel (ROMK) inhibitor with an IC50 of 35 nM. ROMK-IN-32 also inhibits hERG with an IC50 of 22 μM. | |||||||||||||||||||||
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References
Keywords
