1917350-09-4
Chemical Structure
MDM2-p53-IN-16
- CAS No.: 1917350-09-4
- Formula:C32H33N3O5
- Molecular Weight:539.62
IUPAC Name: methyl (2-oxo-2-(2-phenyl-1H-indol-3-yl)acetyl)-L-phenylalanyl-L-leucinate
InChIKey: ANEVZIOZUQXCFC-UIOOFZCWSA-N
SMILES: O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(OC)=O)=O)C(C2=C(C3=CC=CC=C3)NC4=C2C=CC=C4)=O
Biological Activity: MDM2-p53-IN-16 is a MDM2-p53 complex inhibitor with an IC50 value of 4.3 nM to dissociate human p53/MDM2 complex. MDM2-p53-IN-16 reactivates p53, and induces Glioblastoma Multiforme (GBM) cell apoptosis and cell-cycle arrest. MDM2-p53-IN-16 can be used for the cancer research[1].
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MDM2-p53-IN-16 | 99.08% | MDM2-p53-IN-16 is a MDM2-p53 complex inhibitor with an IC50 value of 4.3 nM to dissociate human p53/MDM2 complex. MDM2-p53-IN-16 reactivates p53, and induces Glioblastoma Multiforme (GBM) cell apoptosis and cell-cycle arrest. MDM2-p53-IN-16 can be used for the cancer research. | ||||||||||||||||||||
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Keywords
