1928712-46-2
1928712-46-2
Chemical Structure
SRI-29574
- CAS No.: 1928712-46-2
- Formula:C29H23N5
- Molecular Weight:441.53
IUPAC Name: N-(2,2-diphenylethyl)-2-(imidazo[1,2-a]pyridin-6-yl)quinazolin-4-amine
InChIKey: CLQYCNGZRPKVQF-UHFFFAOYSA-N
SMILES: C1(C2=CN3C(C=C2)=NC=C3)=NC(NCC(C4=CC=CC=C4)C5=CC=CC=C5)=C6C=CC=CC6=N1
Biological Activity: SRI-29574 is an allosteric modulator of the dopamine transporter (DAT). SRI-29574 partially inhibits the uptake of the DAT (IC50=2.3 nM) and also partially inhibits the uptake of the serotonin transporter (SERT) and norepinephrine transporter (NET). SRI-29574 may serve as a useful probe to study the function and regulatory mechanisms of DAT[1].
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SRI-29574 | SRI-29574 is an allosteric modulator of the dopamine transporter (DAT). SRI-29574 partially inhibits the uptake of the DAT (IC50=2.3 nM) and also partially inhibits the uptake of the serotonin transporter (SERT) and norepinephrine transporter (NET). SRI-29574 may serve as a useful probe to study the function and regulatory mechanisms of DAT. | |||||||||||||||||||||
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