1934259-00-3
Chemical Structure
limertinib
Synonym(s): ASK120067
- CAS No.: 1934259-00-3
- Formula:C29H32ClN7O2
- Molecular Weight:546.06
IUPAC Name: N-(5-((5-chloro-4-(naphthalen-2-ylamino)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide
InChIKey: QHPVTCLSVVUPOF-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(NC2=NC=C(C(NC3=CC4=C(C=CC=C4)C=C3)=N2)Cl)=C(C=C1N(CCN(C)C)C)OC)C=C
Biological Activity: limertinib (ASK120067) is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). limertinib is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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limertinib | 99.12% | limertinib (ASK120067) is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). limertinib is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC). | ||||||||||||||||||||
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Keywords
