1945941-09-2
1945941-09-2
Chemical Structure
ADT-007
- CAS No.: 1945941-09-2
- Formula:C26H24FNO5
- Molecular Weight:449.47
InChIKey: CJBUOVAXMPVXFB-UKWGHVSLSA-N
SMILES: O=C(NCC1=CC=CO1)CC2=C(C)/C(C3=CC=C(F)C=C32)=C/C4=CC(OC)=C(C(OC)=C4)O
Biological Activity: ADT-007 is a potent and orally active pan-RAS inhibitor with strong anticancer effects. ADT-007 binds RAS in a nucleotide-free conformation to block GTP activation. ADT-007 potently and selectively inhibits the growth of cancer cells with mutated or hyper-activated wild-type RAS isozymes[1].
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ADT-007 | 99.97% | ADT-007 is a potent and orally active pan-RAS inhibitor with strong anticancer effects. ADT-007 binds RAS in a nucleotide-free conformation to block GTP activation. ADT-007 potently and selectively inhibits the growth of cancer cells with mutated or hyper-activated wild-type RAS isozymes. | ||||||||||||||||||||
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References
Keywords
