194935-38-1
Chemical Structure
Prostaglandin E2 Ethanolamide
Synonym(s): PGE2 ethanolamide
- CAS No.: 194935-38-1
- Formula:C22H37NO5
- Molecular Weight:395.53
IUPAC Name: (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)-N-(2-hydroxyethyl)hept-5-enamide
InChIKey: GKKWUSPPIQURFM-IGDGGSTLSA-N
SMILES: CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)C/C=C\CCCC(NCCO)=O
Biological Activity: Prostaglandin E2 Ethanolamide (PGE2-EA), an analog of PGE2, can be formed enzymatically following COX-2 oxygenation of endocannabinoids. Prostaglandin E2 Ethanolamide (PGE2-EA) could modulate the production of the proinflammatory cytokine TNF-α in human blood and human monocytic cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Prostaglandin E2 Ethanolamide | 99.9% | Prostaglandin E2 Ethanolamide (PGE2-EA), an analog of PGE2, can be formed enzymatically following COX-2 oxygenation of endocannabinoids. Prostaglandin E2 Ethanolamide (PGE2-EA) could modulate the production of the proinflammatory cytokine TNF-α in human blood and human monocytic cells. | ||||||||||||||||||||
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Prostaglandin E2 ethanolamide-d4 | Prostaglandin E2 Ethanolamide-d4 (PGE2 ethanolamide-d4) is the deuterium labeled Prostaglandin E2 Ethanolamide (HY-121996). | |||||||||||||||||||||
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- [1]. Kevin R Kozak, et al. Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. J Biol Chem. 2002 Nov 22;277(47):44877-85. [Content Brief]
- [2]. Kirsten L Brown, et al. Characterisation of the prostaglandin E2-ethanolamide suppression of tumour necrosis factor-α production in human monocytic cells. Biochim Biophys Acta. 2013 Jun;1831(6):1098-107. [Content Brief]
