197960-94-4
Chemical Structure
Ampullosporin A
- CAS No.: 197960-94-4
- Formula:C77H127N19O19
- Molecular Weight:1622.95
InChIKey: QXMNSBVEOAGSSK-WWSPCDPFSA-N
SMILES: CC(C)C[C@@H](CO)NC([C@H](CCC(N)=O)NC(C(C)(C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@H](CCC(N)=O)NC(C(C)(C)NC([C@H](CC(C)C)NC(C(C)(C)NC(C(C)(C)NC([C@H](C)NC([C@@H](NC(C)=O)CC1=CNC2=CC=CC=C12)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: Ampullosporin A is a peptaibol-type polypeptide that can be isolated from the fungus Sepedonium ampullosporum HKI-0053, exhibiting neuroleptic-like activity. Ampullosporin A can inhibit hyperactivity induced by NMDA receptor antagonist MK-801 (HY-15084B) and ameliorate social behavior abnormalities caused by subchronic drug treatment. Ampullosporin A alters the activity of glutamate receptors without affecting dopamine D1 and D2 receptors[1].
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Ampullosporin A | Ampullosporin A is a peptaibol-type polypeptide that can be isolated from the fungus Sepedonium ampullosporum HKI-0053, exhibiting neuroleptic-like activity. Ampullosporin A can inhibit hyperactivity induced by NMDA receptor antagonist MK-801 (HY-15084B) and ameliorate social behavior abnormalities caused by subchronic drug treatment. Ampullosporin A alters the activity of glutamate receptors without affecting dopamine D1 and D2 receptors. | |||||||||||||||||||||
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