1986791-87-0
Chemical Structure
Norbornene-methyl-NHS
- CAS No.: 1986791-87-0
- Formula:C13H15NO5
- Molecular Weight:265.26
IUPAC Name: (2S)-2-(bicyclo[3.1.0]hexan-6-yl)-2-((tert-butoxycarbonyl)amino)acetic acid
InChIKey: PYHZXEKPQIJFQY-UHFFFAOYSA-N
SMILES: O=C(OCC1CC2C=CC1C2)ON3C(CCC3=O)=O
Biological Activity: Norbornene-methyl-NHS is a norbornene-based antibody-drug conjugate linker (ADC Linker) bearing methyl and NHS ester functional groups, which can be used for specific antibody conjugation. Norbornene-methyl-NHS is also a click chemistry reagent containing a TCO group, acting as a dienophile for conjugation via the Diels-Alder reaction, namely the copper-free click reaction with tetrazine[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Norbornene-methyl-NHS | 99.90% | Norbornene-methyl-NHS is a norbornene-based antibody-drug conjugate linker (ADC Linker) bearing methyl and NHS ester functional groups, which can be used for specific antibody conjugation. Norbornene-methyl-NHS is also a click chemistry reagent containing a TCO group, acting as a dienophile for conjugation via the Diels-Alder reaction, namely the copper-free click reaction with tetrazine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
