1995132-67-6
1995132-67-6
Chemical Structure
HSP90-IN-14
- CAS No.: 1995132-67-6
- Formula:C14H8Cl2N4O4S
- Molecular Weight:399.21
IUPAC Name: 2-((2-(4,5-dichloro-1H-pyrrole-2-carboxamido)benzo[d]thiazol-6-yl)amino)-2-oxoacetic acid
InChIKey: QJHQNFJZFZLWJA-UHFFFAOYSA-N
SMILES: O=C(O)C(NC1=CC=C2N=C(NC(C3=CC(Cl)=C(Cl)N3)=O)SC2=C1)=O
Biological Activity: HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively[1].
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HSP90-IN-14 | HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively. | |||||||||||||||||||||
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References
Keywords
