HSP90-IN-14
HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively.
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- CAS 番号: 1995132-67-6
- 分子式: C14H8Cl2N4O4S
- 分子量:399.21
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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HSP90β 0.26 ± 0.0 μM (Kd) |
HSP90-IN-14 (compound 4) (50 µM) inhibits influenza virus-induced cytopathic effect at non-toxic concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1995132-67-6
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分子量 399.21
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分子式 C14H8Cl2N4O4S
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SMILES
O=C(O)C(NC1=CC=C2N=C(NC(C3=CC(Cl)=C(Cl)N3)=O)SC2=C1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HSP90-IN-14 関連分類
HY-147974 関連分類
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