HSP90-IN-14
HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1995132-67-6
- Formula: C14H8Cl2N4O4S
- Molecular Weight:399.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HSP90β 0.26 ± 0.0 μM (Kd) |
HSP90-IN-14 (compound 4) (50 µM) inhibits influenza virus-induced cytopathic effect at non-toxic concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1995132-67-6
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Molecular Weight 399.21
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Formula C14H8Cl2N4O4S
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SMILES
O=C(O)C(NC1=CC=C2N=C(NC(C3=CC(Cl)=C(Cl)N3)=O)SC2=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HSP90-IN-14 Related Classifications
HY-147974 Related Classifications
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