199656-46-7
Chemical Structure
CP-465022 maleate
- CAS No.: 199656-46-7
- Formula:C30H28ClFN4O5
- Molecular Weight:579.02
IUPAC Name: (E)-3-(2-chlorophenyl)-2-(2-(6-((diethylamino)methyl)pyridin-2-yl)vinyl)-6-fluoroquinazolin-4(3H)-one maleate
InChIKey: WLLUWLRVXIHECY-KSUUAYPFSA-N
SMILES: O=C1N(C2=CC=CC=C2Cl)C(/C=C/C3=NC(CN(CC)CC)=CC=C3)=NC4=C1C=C(F)C=C4.O=C(O)/C=C\C(O)=O
Biological Activity: CP-465022 Maleate is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes[1][2].
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CP-465022 maleate | CP-465022 Maleate is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes. | |||||||||||||||||||||
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Keywords